Aim.To study the effect of multiagent chemotherapy on structural and functional vascular, electrophysiological parameters and cardiac hemodynamics in patients with stomach cancer.Material and methods.The study included 3 groups of 25 people: healthy volunteers, those with established cardiac disease (hypertension + coronary artery disease), gastric
The immune checkpoint adenosine 2A receptor is associated with aggressive clinical outcomes and reflects an immunosuppressive tumor microenvironment in human breast cancer
BackgroundThe crosstalk between the immune system and cancer cells has aroused considerable interest over the past decades.To escape immune surveillance cancer cells evolve various strategies orchestrating tumor microenvironment.The discovery of the inhibitory immune checkpoints was a major breakthrough Fruit Formulas due to their crucial contribut
Giant cell arteritis. Part I. Terminology, classification, clinical manifestations, diagnosis
Giant cell arteritis (GCA) is a vasculitis affecting mainly large and medium-sized arteries, which the classification of systemic vasculitides refers to as those mainly involving the large vessels.GCA is typified by the involvement of extracranial aortic branches and intracranial vessels, the aorta and its large vessels are being affected most freq
A rare case of traumatic subretinal migration of crystalline lens, corroborated histologically
Blunt trauma is the most common cause of posterior dislocation of the crystalline lens.We describe KERATIN COND a rare case of subretinal migration of crystalline lens through the giant retinal tear following blunt ocular trauma.This incidental finding of subretinal dislocation of lens following blunt ocular trauma was confirmed on histopathologica
Protracted Clonal Trajectory of a JAK2 V617F-Positive Myeloproliferative Neoplasm Developing during Long-Term Remission from Acute Myeloid Leukemia
Although transformation of the myeloproliferative neoplasms (MPNs) to acute myeloid leukemia (AML) is well documented, development ORG SMALL LIMA BEANS of an MPN in patients previously treated for, and in remission from, AML is exceedingly rare.A case is described in which a patient was successfully treated for AML and in whom a JAK2 V617F-positive